New Evidence Strengthens the Link Between Hypothalamic Injury, Obesity, and Insulin Resistance
/
0 Comments
Obesity involves changes in the function of brain regions that
regulate body fatness and blood glucose, particularly a region called
the hypothalamus. My colleagues and I previously showed that obesity is
associated with inflammation and injury of the hypothalamus in rodent
models, and we also presented preliminary evidence that the same might
be true in humans. In our latest paper, we confirm this association,
and show that hypothalamic injury is also associated with a marker of
insulin resistance, independently of BMI.